Some of the mutations you get from getting exposed to radiation can be very beneficial depending on your build.
I haven’t verified this, but the Emmett Mountain Disposal Site supposedly has a rad shower right next to a bunch of radioactive barrels. So you can alternate between the radiation and the shower until you get the mutation you want. Then, you can equip a level 2 Starched Genes (Luck) perk card to keep the mutation from being cured.
I’m planning to try and pick up the Twisted Muscles (25% melee damage) mutation to make the already OP melee build even better.